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    首頁(yè) /診斷試劑 /熱門(mén)腫瘤標志物 /TMB /tTMB-P6(8.98) Reference Standard

    tTMB-P6(8.98) Reference Standard

    CBP80001-6

    產(chǎn)品描述
    產(chǎn)品數據庫
    I. Background

    Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials.

     

    Sample ID

    Cat.No.

    Background

    Assay

    Comments

    DC198N0167

    CBP80001-6N

    B lymphoblast, Female

    500x WES

    Same individual

     

    DC198N0166

    CBP80001-6T

    Breast Cancer, Female

    500x WES
    IDT xGenExome Research Panel v1.0捕獲，Target Region 39M, Probe Region 51M, CDS Region 33.52M;
    HiSeq X-TEN，af選擇0.02 cut off，再過(guò)濾。
    DC198N0166 is 100% Tumor sample.

     

    　

    Cut off =2%

    Cut off =3%

    Cut off =4%

    Cut off =5%

    Mutation Number

    301

    275

    259

    254

    TMB value

    8.98

    8.20

    7.73

    7.58 

     

    計算數據下載：DC198N0166.tmb
     
     
     
     

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