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    首頁(yè) /診斷試劑 /熱門(mén)腫瘤標志物 /TMB /tTMB-P8(27.15) Reference Standard

    tTMB-P8(27.15) Reference Standard

    CBP80001-8

    產(chǎn)品描述
    產(chǎn)品數據庫
    I. Background

    Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials.

     

    Sample ID

    Cat.No.

    Background

    Assay

    Comments
    DC198N0165
    		 CBP80001-8N B lymphoblast, Female 500x WES

     Same individual

    DC198N0164

    CBP80001-8T

    Ductal breast carcinoma, Female

    500x WES
    IDT xGenExome Research Panel v1.0捕獲，Target Region 39M, Probe Region 51M, CDS Region 33.52M;
    HiSeq X-TEN，af選擇0.02 cut off，再過(guò)濾。
    DC198N0164 is 100% Tumor sample.

     

    　

    Cut off =2%

    Cut off =3%

    Cut off =4%

    Cut off =5%

    Mutation Number

    910

    840

    766

    685

    TMB value

    27.15

    25.06

    22.85

    20.44 

     

    計算數據下載：DC198N0164.tmb
     
     
     
     

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