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    首頁(yè) /藥靶模型 /激酶靶點(diǎn) /c-Kit /c-Kit Y823D/BaF3

    c-Kit Y823D/BaF3

    CBP73208

    產(chǎn)品描述
    產(chǎn)品數據庫
    I. Introduction

    Cell Line Name:

    c-Kit Y823D/BaF3

    Gene Synonyms:

    c--Kit 

    Host Cell:

    Ba/F3

    Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

    Freeze Medium:

    90% FBS+10% DMSO

    Complete Culture Medium:

    RPMI-1640+10%FBS

    Mycoplasma Status:

    Negative

     

    II. Background

     

    KIT Y823D lies within the protein kinase domain of the Kit protein (UniProt.org). Y823D confers a gain of function on Kit, as indicated by constitutive phosphorylation of Kit in cultured cells (PMID: 14695343, PMID: 20633291).

     
    III. Representative Data

    1.WB of  c-Kit Y823D/BaF3

    2.Sanger of c-Kit Y823D/BaF3

    3. Anti-proliferation assay

    Figure 3. CTG Proliferation Assay of BaF3 c-KIT Y823D (C1).

     


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