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    首頁(yè) /藥靶模型 /激酶靶點(diǎn) /c-Kit /c-Kit L576P/BaF3

    c-Kit L576P/BaF3

    CBP73298

    產(chǎn)品描述
    產(chǎn)品數據庫
    I. Background

    KIT L576P lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 17372901). L576P confers a gain of function to Kit, as indicated by constitutive phosphorylation of Kit, and is transforming in cell culture (PMID: 17372901).

     
    II. Introduction

    Cell Line Name:

    c-Kit L576P/BaF3

    Host Cell:

    Ba/F3

    Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

    Application:

    Anti-proliferation assay and PD assay

    Freeze Medium:

    90% FBS+10% DMSO

    Complete Culture Medium:

    RPMI-1640+10%FBS

    Mycoplasma Status:

    Negative

     
    III. Representative Data

    1. WB of c-Kit L576P/BaF3

     

    2. Sanger of c-Kit L576P/BaF3

    3. Anti-proliferation assay

    Figure 3. CTG Proliferation Assay of BaF3 c-KIT L576P (C6).


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