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    首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細胞 /Orphan and other 7TM /GPR55 Reporter cell

    GPR55 Reporter cell

    CBP71431

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    I. Background
    GPR55 is a class A orphan G protein-coupled receptor that has drawn important therapeutic attention in the last decade because of its role in pathophysiological processes including vascular functions, metabolic dysfunction, neurodegenerative disorders, or bone turnover among others. 
     
    II. Introduction
    Expressed gene: GPR55
    Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium: 90% FBS+10% DMSO
    Culture Medium: DMEM+10%FBS+2ug/ml puromycin+200ug/ml hygromycin
    Mycoplasma Testing: Negative
    Storage: Liquid nitrogen
    Application(s): Functional assay for GPR55
    Transducer: Gq+G12/13 
     
    Ⅲ. Representative Data

    Figure 1. Dose Response of Agonists in GPR55 Reporter Cell Line(C7).

     

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