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    首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細胞 /Class A(Rhodopsin) /CXCR5/CHO

    CXCR5/CHO

    CBP71370

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    I. Background
    CXCR5 (C-X-C Motif Chemokine Receptor 5) is a Protein Coding gene. Diseases associated with CXCR5 include Intraocular Lymphoma and Lymphoma. Among its related pathways are CCR5 Pathway in Macrophages and Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and C-X-C chemokine receptor activity. 
     
    II. Introduction
    Host Cell:

    CHO

    Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium: 90% FBS+10% DMSO
    Culture Medium: F12K+10%FBS+5ug/ml puromycin
    Mycoplasma Status: Negative
    Storage: Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for CXCR5

    Transducer: Gi
     
    Ⅲ. Description of Host Cell Line
    Organism: Hamster
    Tissue: Ovary
    Morphology: Epithelial
    Growth Properties: Adherent
     
    Ⅳ. Representative Data

    Figure 1. Recombinant CXCR5/CHO cell line expressing CXCR5.

    Figure 2. RD CXCL13 effect on CHO-CXCR5 clone 5.


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