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    首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細胞 /Class A(Rhodopsin) /AGTR1/CHO

    AGTR1/CHO

    CBP71314

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    I. Background

    AGTR1 (Angiotensin II Receptor Type 1) is a Protein Coding gene. Diseases associated with AGTR1 include Renal Tubular Dysgenesis and Hypertension, Essential. Among its related pathways are Signaling by GPCR and ADP signalling through P2Y purinoceptor 1. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and angiotensin type II receptor activity.

     
    II. Introduction
    Host Cell:

    CHO

    Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium: 90% FBS+10% DMSO
    Culture Medium: F12K+10%FBS+5ug/ml puromycin
    Mycoplasma Status: Negative
    Storage: Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assays for AGTR1

    Transducer: Gq
     
    Ⅲ. Description of Host Cell Line
    Organism: Hamster
    Tissue: Ovary
    Morphology: Epithelial
    Growth Properties: Adherent
     
    Ⅳ. Representative Data

    Figure 1. HTRF IP One Assay with AGTR1(AT1) CHO Cells(C18).


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