309?Gene?Plus?TMB?Panel
CBPF0002
產(chǎn)品描述
產(chǎn)品數據庫
| 309 Gene Plus TMB Panel | ||||||||
| Descripition | 此實(shí)體瘤泛癌種Panel包含下列309個(gè)基因的全部編碼區，5個(gè)常見(jiàn)實(shí)體瘤的融合基因熱點(diǎn)內含子區域，99個(gè)微衛星不穩定檢測位點(diǎn)，覆蓋基因組約0.86Mb區域，支持包括堿基替換、插入、缺失檢測分析。 | |||||||
| 309個(gè)基因：含全部外顯子區域 | ||||||||
| ABL1 | CBFB | DNMT3A | GABRA6 | SMO | MAP2K2 | CEBPA | RAD52 | INPP4B |
| C11ORF30 | DAXX | FLT1 | KIT | AURKA | NOTCH3 | FANCC | TEK | MKNK1 |
| CUL3 | FGFR3 | KDM6A | MYD88 | CDK12 | PTPN11 | HNF1A | BRCA2 | PBRM1 |
| FGF4 | JAK3 | MUTYH | POLE | ERBB3 | SPEN | MCL1 | CRKL | RBM10 |
| IRF4 | MSH6 | PIK3R1 | SMAD2 | GNA11 | BARD1 | NTRK2 | FGF10 | TNFRSF14 |
| MPL | PIK3C2B | SDHD | ZNF703 | LTK | CDKN1B | RAD51 | IDH2 | BTK |
| PDCD1LG2 | RPTOR | WT1 | ASXL1 | NFKBIA | ESR1 | STK11 | MEN1 | CTNNB1 |
| RET | VEGFA | AR | CD79A | PRKAR1A | GSK3B | BCOR | PARP1 | FGF3 |
| TSC1 | ALK | CCNE1 | EPHA3 | SNCAIP | MAP2K4 | CHEK1 | RAD54L | IRF2 |
| ACVR1B | CBL | DOT1L | GATA3 | AURKB | NPM1 | FANCG | TET2 | MLH1 |
| CALR | DDR1 | FLT3 | KLHL6 | CDK4 | PTPRO | HRAS | BRD4 | PDCD1 |
| CUL4A | FGFR4 | KDR | NBN | ERBB4 | SPOP | MDM2 | CSF1R | REL |
| FGF6 | JUN | MYC | PPARG | GNA13 | BCL2 | NTRK3 | FGF12 | TP53 |
| IRS2 | MST1R | PIM1 | SMAD4 | LYN | CDKN2A | RAD51B | IGF1R | |
| MRE11A | PIK3C2G | SETD2 | ATM | NKX2-1 | EZH2 | SUFU | MERTK | |
| PDGFRA | SDHA | XPO1 | CD79B | PRKCI | H3F3A | BCORL1 | PARP2 | |
| RICTOR | VHL | ARAF | EPHB1 | SOCS1 | MAP3K1 | CHEK2 | RAF1 | |
| TSC2 | ALOX12B | CD22 | GATA4 | AXIN1 | NRAS | FANCL | TGFBR2 | |
| AKT1 | CCND1 | EED | KMT2A | CDK6 | QKI | HSD3B1 | BRIP1 | |
| CARD11 | DDR2 | FOXL2 | NF1 | ERCC4 | SRC | MDM4 | CSF3R | |
| CXCR4 | FH | KEAP1 | PPP2R1A | GNAQ | BCL2L1 | P2RY8 | FGF14 | |
| FGFR1 | KDM5A | MYCL | SMARCA4 | MAF | CDKN2B | RAD51C | IKBKE | |
| JAK1 | MTAP | PMS2 | ATR | NOTCH1 | FAM46C | SYK | MET | |
| MSH2 | PIK3CA | SF3B1 | CDC73 | PTCH1 | HDAC1 | BRAF | PARP3 | |
| PDGFRB | SDHB | XRCC2 | EPHB4 | SOX2 | MAP3K13 | CIC | RARA | |
| RNF43 | WHSC1 | ARFRP1 | GATA6 | AXL | NT5C2 | FAS | TIPARP | |
| TYRO3 | AMER1 | CD274 | KMT2D | CDK8 | RAC1 | ID3 | BTG1 | |
| AKT2 | CCND2 | EGFR | NF2 | ERG | STAG2 | MED12 | CTCF | |
| CASP8 | DIS3 | FUBP1 | PPP2R2A | GNAS | BCL2L2 | PALB2 | FGF19 | |
| CYP17A1 | FLCN | KEL | SMARCB1 | MAP2K1 | CDKN2C | RAD51D | IKZF1 | |
| FGFR2 | KDM5C | MYCN | ATRX | NOTCH2 | FANCA | TBX3 | MITF | |
| JAK2 | MTOR | POLD1 | CDH1 | PTEN | HGF | BRCA1 | PAX5 | |
| MSH3 | PIK3CB | SGK1 | ERBB2 | SOX9 | MAPK1 | CREBBP | RB1 | |
| PDK1 | SDHC | ZNF217 | GID4 | BAP1 | NTRK1 | FBXW7 | TNFAIP3 | |
| ROS1 | WHSC1L1 | ARID1A | KRAS | CDKN1A | RAD21 | IDH1 | BTG2 | |
| U2AF1 | APC | CD70 | NFE2L2 | ERRFI1 | STAT3 | MEF2B | CTNNA1 | |
| AKT3 | CCND3 | EP300 | PRDM1 | GRM3 | BCL6 | PARK2 | FGF23 | |
| 5個(gè)融合基因區域：部分內含子區域 | ||||||||
| NTRK1 | intron9;10 | |||||||
| ALK | intron17;18;19;20;21 | |||||||
| ROS1 | intron33 | |||||||
| RET | intron11 | |||||||
| FGFR3 | intron14;16;17 | |||||||
| 99個(gè)微衛星不穩定位點(diǎn) | ||||||||
| BAT26 | 2B3D NCI Panel(CSCO指南);Promega Panel | |||||||
| BAT25 | 2B3D NCI Panel(CSCO指南);Promega Panel | |||||||
| D5S346 | 2B3D NCI Panel(CSCO指南) | |||||||
| D2S123 | 2B3D NCI Panel(CSCO指南) | |||||||
| D17S250 | 2B3D NCI Panel(CSCO指南) | |||||||
| NR21 | Promega Panel | |||||||
| NR24 | Promega Panel | |||||||
| NR27 | Promega Panel | |||||||
| MONO27 | Promega Panel | |||||||
| MSI:10-99 | 額外已驗證的89個(gè)微衛星位點(diǎn) | |||||||
| Product Information | ||||||||
| Intended Use | Research Use Only | |||||||
| Unit Size | 96 rxn | |||||||
| Storage | -25 ~ -15°C | |||||||
| Expiry | 12 months from the date of manufacture | |||||||
